The present study aims at preparing an Emulgel formulation of Meloxicam using emulsifiers and various gelling agents along with the use of. PDF | Emulgel is one of the recent technologies in NDDS used for dual control release of emulsion and gel for topical use. The stability of. PDF | Topical therapies in cream, ointment, gel and lotion formulation, are an important component of dermatological therapeutic.

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Blackwell Scientific Publications; This study emupgel conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: Preparation of an emulgel for treatment of aphthous ulcer on the basis of carbomers. Support Center Support Center. Published online Sep 1.

Rheological studies revealed that the CHL emulgels exhibited a shear-thinning behavior with thixotropy.

Formulation and evaluation of topical preparations containing phenol and local vesicants. Author information Article notes Copyright formulaton License information Disclaimer. Commercially available CHL topical powder was used for comparison. The prepared emulgels were evaluated for their physical appearance, rheological behavior, drug release, antifungal activity, and stability. Received Dec 31; Accepted May The influence of the type of the gelling agent and the concentration of both the oil phase and emulsifying agent on the drug release from the prepared emulgels was investigated using a 2 3 factorial design.


Transdermal controlled release systems. Formulation and stability of chloramphenicol gel and emulgel. Analysis of data on the medicament release from ointments.

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Abstract This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: All the prepared emulgels showed acceptable physical properties concerning color, homogeneity, consistency, spreadability, and pH value. It was found that the emulsifying agent concentration had the most pronounced effect on the formulatino release from the emulgels followed by the oil phase concentration and finally the type of the gelling agent.

The Theory and Practice of Industrial Pharmacy. Lea and Febiger; They also exhibited higher drug release and antifungal activity than the CHL powder. A study of shear and compression deformations on hydrophilic gels of tretinoin. Marcel Dekker Inc; Az J Pharm Sci. Stability studies showed that the physical appearance, rheological properties, drug release, and antifungal activity in all the prepared emulgels remained unchanged upon storage for 3 months.


As a general conclusion, it was suggested that the CHL emulgel formulation prepared with HPMC with the oil phase concentration in its fmulgel level and emulsifying agent concentration in its high level was the formula of choice since it showed the highest drug release and antifungal activity.

This article has been cited by other articles in PMC.

Optimization of chlorphenesin emulgel formulation

Bioavailability of salbutamol sulphate from different suppository formulations. The Pharmaceutical Press; Egypt J Pharm Sci.

Please review our privacy policy. Swarbrick J, Boylan JC, editors. Medical Applications of Controlled Release. National Center for Biotechnology InformationU.

Optimization of chlorphenesin emulgel formulation

The drug release from all the emulgels was found to follow diffusion-controlled mechanism. The Complete Drug Reference.

Development of a thermoreversible gel for controlled-release ocular delivery of diclofenac sodium. Encyclopedia of Pharmaceutical Technology.